TXA709 inhibits the function of FtsZ. Pilch said that TXA709 kills MRSA bacteria in a unique manner, inhibiting the function of a protein, FtsZ, essential for the bacteria to divide and survive. By combining TXA709 with cefdinir, a cephalosporin antibiotic that acts much like penicillin, scientists were able to lower the dosage of the new ...Jun 1, 2023 · Many medications are available to treat COVID-19, including oral treatments like Paxlovid (nirmatrelvir / ritonavir) and Lagevrio (molnupiravir). In late May 2023, the FDA fully approved Paxlovid for COVID-19. It’s the first oral antiviral that is approved to treat the condition. It was previously only available for emergency use. Chloroquine and nelfinavir were used as positive controls. Results: We revealed that the tested antibiotics exert strong capacity for binding to COVID-19 Main Protease (M pro). According to the results obtained from the GOLD docking program, ciprofloxacin and moxifloxacin bind to the protein active site more strongly than the native ligand.Cefdinir is a cephalosporin (SEF a low spor in) antibiotic that is used to treat many different types of infections caused by bacteria. Cefdinir may also be used for purposes not listed in this ...The most common symptoms of COVID-19 are a fever, coughing, and breathing problems. Unless you have severe symptoms, you can most likely treat them at home, the way you would for a cold or the flu ...Covid-19 Self test kits; Oxygen Cans & Concentrators; ... Cefdinir is used in the treatment of bacterial infections. How Cefdinir works. Cefdinir is an antibiotic. It ...Massachusetts General Hospital (MGH) COVID-19 Treatment Guidance (11) If empirical antibiotics are indicated, the recommendation is for: • Doxycycline 100 mg PO BID x 5 days or Azithromycin 500 mg PO x 1 then 250 mg PO daily for 4 days along with Ceftriaxone 1 gm IV daily. • For nonpregnant patients, doxycycline is preferred over azithromycin.Oct 26, 2020 · Three drugs identified. After using LBVS to study approximately 4,000 drugs, then verifying their findings, the scientists identified three that may be effective against COVID-19 and, in their ... And, when used under the conditions described in the EUA to treat COVID-19, the known and potential benefits of baricitinib outweigh the known and potential risks for the drug. There are no ... Cefdinir is a cephalosporin (SEF a low spor in) antibiotic that is used to treat many different types of infections caused by bacteria. Cefdinir may also be used for purposes not listed in this medication guide.Chloroquine and nelfinavir were used as positive controls. Results: We revealed that the tested antibiotics exert strong capacity for binding to COVID-19 Main Protease (M pro). According to the results obtained from the GOLD docking program, ciprofloxacin and moxifloxacin bind to the protein active site more strongly than the native ligand. Oct 9, 2020 · These include people with expertise and experience of treating patients for the specific health conditions covered by the guidance during the current COVID-19 pandemic. We developed this guideline using the interim process and methods for developing rapid guidelines on COVID-19 in response to the rapidly evolving situation. Covid-19 Self test kits; Oxygen Cans & Concentrators; ... Cefdinir is used in the treatment of bacterial infections. How Cefdinir works. Cefdinir is an antibiotic. It ...Azithromycin use was associated with a reduction in mortality and ventilation days in other viral infections. These properties could be beneficial throughout the COVID-19. However, the evidence of its use is scarce and of low quality. Azithromycin has been assessed in retrospective observational studies mainly in combination with ...efficacy of Omnicef in neonates and infants less than six months of age have. not been established. To reduce the development of drug-resistant bacteria. and maintain the effectiveness of Omnicef and other antibacterial drugs, Omnicef should be used only to treat or prevent infections that are proven or. strongly suspected to be caused by bacteria.Satisfaction. For me Cefdinir was worse than the infection. It felt like my entire digestive system had been chemically burned from my throat to intestines and bladder. It didn't feel like a UTI it felt like a chemical burn. It gave me a headache, stomach pain, belly pain and pain urinating.There are currently two oral antiviral pills, Paxlovid and Lagevrio, authorized for emergency use for the treatment of certain patients with mild to moderate COVID-19. Data have shown that the use ...Penicillin allergy: Cefpodoxime, 10 mg per kg orally per day for 10 to 14 days. Cefdinir , 14 mg per kg per day orally, divided in one to two doses for 10 to 14 days. Acute otitis media. First ...Antibiotics commonly prescribed to treat staph infections include cefazolin, nafcillin, oxacillin, vancomycin, daptomycin and linezolid. For serious staph infections, vancomycin may be required. This is because so many strains of staph bacteria have become resistant to other traditional antibiotics. This means other antibiotics can no longer ...Three drugs identified. After using LBVS to study approximately 4,000 drugs, then verifying their findings, the scientists identified three that may be effective against COVID-19 and, in their ...Sep 11, 2022 · Examples include ceftriaxone (Rocephin), piperacillin-tazobactam, cefepime (Maxipime ), ceftazidime (Fortaz) , vancomycin (Firvanq) , ciprofloxacin (Cipro), and levofloxacin (Levaquin). If you ... COVID-19; Diabetes; Environment & Sustainability; Exercise & Fitness; Eye Health; ... In children ages 6 months to 12 years, cefdinir is also used to treat otitis media (middle ear infection).Aug 4, 2023 · Common side effects of cefdinir may include: nausea, vomiting, stomach pain, diarrhea; vaginal itching or discharge; headache; or. rash (including diaper rash in an infant taking liquid cefdinir. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol, remdesivir, and favipiravir are currently undergoing clinical studies to test their efficacy and safety in the treatment of coronavirus disease 2019 (COVID-19) in China; some promising results have been achieved thus far. And, when used under the conditions described in the EUA to treat COVID-19, the known and potential benefits of baricitinib outweigh the known and potential risks for the drug. There are no ...Massachusetts General Hospital (MGH) COVID-19 Treatment Guidance (11) If empirical antibiotics are indicated, the recommendation is for: • Doxycycline 100 mg PO BID x 5 days or Azithromycin 500 mg PO x 1 then 250 mg PO daily for 4 days along with Ceftriaxone 1 gm IV daily. • For nonpregnant patients, doxycycline is preferred over azithromycin.The drug distributes into various tissues (e.g. sinus and tonsil) and fluids (e.g. middle ear), and has a pharmacokinetic profile that allows for once- or twice-daily administration.Cefdinir, administered for 5 or 10 days, has shown good clinical and bacteriological efficacy in the treatment of a wide range of mild-to-moderate infections of the ... Notwithsanding the absence of evidence of clinical efficacy, these drugs are widely used outside of clinical trials (off label) for prophylaxis and treatment of this viral infection. The rationale behind the prescription of macrolide antibiotics (azithromycin) for Covid-19 is obscure as well.Sep 11, 2022 · Examples include ceftriaxone (Rocephin), piperacillin-tazobactam, cefepime (Maxipime ), ceftazidime (Fortaz) , vancomycin (Firvanq) , ciprofloxacin (Cipro), and levofloxacin (Levaquin). If you ... Penicillin allergy: Cefpodoxime, 10 mg per kg orally per day for 10 to 14 days. Cefdinir , 14 mg per kg per day orally, divided in one to two doses for 10 to 14 days. Acute otitis media. First ...Sep 29, 2021 · Sulfasalazine (Azulfidine), used to treat Crohn's disease, ulcerative colitis and rheumatoid arthritis; Dapsone, used to treat leprosy, dermatitis and certain types of pneumonia; Keep in mind that if you have a reaction to a sulfonamide antibiotic, you may still be able to take other sulfonamide medications without having a reaction. The drug distributes into various tissues (e.g. sinus and tonsil) and fluids (e.g. middle ear), and has a pharmacokinetic profile that allows for once- or twice-daily administration.Cefdinir, administered for 5 or 10 days, has shown good clinical and bacteriological efficacy in the treatment of a wide range of mild-to-moderate infections of the ... Treatment of adults with a current diagnosis of mild-to-moderate COVID-19 who are at high risk for progression to severe COVID-19, including hospitalization or death and forJun 2, 2021 · Background Empiric antibiotics for community acquired bacterial pneumonia (CABP) are often prescribed to patients with COVID-19, despite a low reported incidence of co-infections. Stewardship interventions targeted at facilitating appropriate antibiotic prescribing for CABP among COVID-19 patients are needed. Amoxicillin and clavulanate combination is used to treat bacterial infections in many different parts of the body (eg, ear, lungs, sinus, skin, urinary tract). Amoxicillin and clavulanate combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors.Satisfaction. For me Cefdinir was worse than the infection. It felt like my entire digestive system had been chemically burned from my throat to intestines and bladder. It didn't feel like a UTI it felt like a chemical burn. It gave me a headache, stomach pain, belly pain and pain urinating.SARS-CoV-2, which causes COVID-19, is a virus, and therefore antibiotics will not treat a coronavirus infection. Sometimes, people with COVID-19 develop other infections. Even then, it is ...Use: For the treatment of mild to moderate COVID-19 in adults who are at high risk for progression to severe COVID-19, including hospitalization or death. Usual Pediatric Dose for COVID-19 (EUA) For investigational use only Use: Patients 12 to 18 years old weighing at least 40 kg: Nirmatrlvir: 300 mg orally twice a day Ritonavir: 100 mg orally ...May 1, 2023 · Precautions. If your symptoms do not improve within a few days, or if they become worse, check with your doctor. Cefdinir may cause diarrhea, and in some cases it can be severe. Do not take any medicine or give medicine to your child to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or ... Sep 11, 2022 · Examples include ceftriaxone (Rocephin), piperacillin-tazobactam, cefepime (Maxipime ), ceftazidime (Fortaz) , vancomycin (Firvanq) , ciprofloxacin (Cipro), and levofloxacin (Levaquin). If you ... Background Empiric antibiotics for community acquired bacterial pneumonia (CABP) are often prescribed to patients with COVID-19, despite a low reported incidence of co-infections. Stewardship interventions targeted at facilitating appropriate antibiotic prescribing for CABP among COVID-19 patients are needed.Paxlovid (nirmatrelvir / ritonavir; co-packaged) - approved as an oral antiviral treatment for certain adults. It is used for the treatment of mild to moderate COVID-19 in adults who are at high risk for progression to severe COVID-19, including hospitalization or death. Paxlovid is not approved for use as pre-exposure or post-exposure ...And, when used to treat COVID-19 for the authorized population, the known and potential benefits of Actemra outweigh the known and potential risks for the drug. There are no adequate, approved and ...Sulfasalazine (Azulfidine), used to treat Crohn's disease, ulcerative colitis and rheumatoid arthritis; Dapsone, used to treat leprosy, dermatitis and certain types of pneumonia; Keep in mind that if you have a reaction to a sulfonamide antibiotic, you may still be able to take other sulfonamide medications without having a reaction.Clindamycin. Cephalexin is a cephalosporin-type antibiotic that may be used in the treatment of infections caused by susceptible gram-positive bacteria. Approximately 10% of people who are allergic to penicillin... more. Clindamycin is an antibiotic that is usually reserved for treating anaerobic infections or other serious infections caused by ...Oct 1, 2020 · In conclusion, this is an executive summary of a multidisciplinary guideline with recommendations for the empirical antibacterial treatment of hospitalized adults with a respiratory infection and proven or high likelihood of COVID-19. Such recommendations on treatment in COVID-19 patients need to be updated regularly, as the evidence on ... Jul 14, 2023 · The FDA also has authorized COVID-19 convalescent plasma therapy with high antibody levels to treat COVID-19. Convalescent plasma is blood donated by people who've recovered from COVID-19. Convalescent plasma with high antibodies may be used to help people diagnosed with COVID-19 who have weakened immune systems. This medication is used to treat coughs caused by the common cold and other breathing problems (such as pneumonia, bronchitis, emphysema, asthma).May 19, 2023 · COVID-19 rashes. Skin rashes are now associated with coronavirus COVID-19 infections. Similar to other viral diseases such as HIV and bacterial diseases like syphilis, COVID-19 rashes can take many different forms. One study from Spain identified five different patterns of COVID-19 rash. The most common type was a "maculopapular rash." COVID-19 rashes. Skin rashes are now associated with coronavirus COVID-19 infections. Similar to other viral diseases such as HIV and bacterial diseases like syphilis, COVID-19 rashes can take many different forms. One study from Spain identified five different patterns of COVID-19 rash. The most common type was a "maculopapular rash."Jul 14, 2023 · The FDA also has authorized COVID-19 convalescent plasma therapy with high antibody levels to treat COVID-19. Convalescent plasma is blood donated by people who've recovered from COVID-19. Convalescent plasma with high antibodies may be used to help people diagnosed with COVID-19 who have weakened immune systems. Azithromycin is used to treat certain bacterial infections in many different parts of the body. This medicine may mask or delay the symptoms of syphilis. It is not effective against syphilis infections. Azithromycin belongs to the class of drugs known as macrolide antibiotics. It works by killing bacteria or preventing their growth.Cefdinir (brand name Omnicef has been discontinued) is an antibiotic used to treat bacterial infections such as strep throat, E. coli, staph infections, streptococcus infections , ear infections, tonsillitis, bronchitis, and pneumonia. The most common side effects include. nausea.Kory recommends a weekly dose of ivermectin to prevent COVID-19 infection. "He paints himself as a savior, which then implies that every other doctor is not a savior," Dr. Graham Walker, a San ...Penicillin allergy: Cefpodoxime, 10 mg per kg orally per day for 10 to 14 days. Cefdinir , 14 mg per kg per day orally, divided in one to two doses for 10 to 14 days. Acute otitis media. First ...Omnicef; Descriptions. Cefdinir is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.No safety issues were noted with use of doxycycline.Doxycycline is an attractive candidate as a repurposed drug in the treatment of COVID-19 infection, with an established safety profile, strong preclinical rationale, and compelling initial clinical experience described here. The reviews of this paper are available via the supplemental material ...Hydroxychloroquine. The drug hydroxychloroquine received a lot of attention at the beginning of the pandemic as a possible way to treat COVID-19. At one time used as an anti-malarial drug, it’s ...Cefdinir is a cephalosporin (SEF a low spor in) antibiotic that is used to treat many different types of infections caused by bacteria. Cefdinir may also be used for purposes not listed in this medication guide.CEFDINIR (SEF di ner) treats infections caused by bacteria. It belongs to a group of medications called cephalosporin antibiotics. It will not treat colds, the flu, or infections caused by viruses. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME (S): Omnicef ...Mar 14, 2023 · Talk to your health care professional about available treatment options if you have COVID-19. Your provider will know the best option for you based on your symptoms, risks and health history. Answer From Daniel C. DeSimone, M.D. The FDA has approved an antiviral drug called remdesivir (Veklury) to treat COVID-19 in adults and children who are age 12 and older. Remdesivir may be prescribed for people who are hospitalized with COVID-19 and need supplemental oxygen or have a higher risk of serious illness.Background Empiric antibiotics for community acquired bacterial pneumonia (CABP) are often prescribed to patients with COVID-19, despite a low reported incidence of co-infections. Stewardship interventions targeted at facilitating appropriate antibiotic prescribing for CABP among COVID-19 patients are needed.Hydroxychloroquine and chloroquine are oral medications that doctors use to treat malaria. In March 2020, the FDA issued an EUA for both drugs to treat COVID-19. However, they revoked this ...Examples include ceftriaxone (Rocephin), piperacillin-tazobactam, cefepime (Maxipime ), ceftazidime (Fortaz) , vancomycin (Firvanq) , ciprofloxacin (Cipro), and levofloxacin (Levaquin). If you ...Cefdinir is a cephalosporin (SEF a low spor in) antibiotic that is used to treat many different types of infections caused by bacteria. Cefdinir may also be used for purposes not listed in this ...There are currently two oral antiviral pills, Paxlovid and Lagevrio, authorized for emergency use for the treatment of certain patients with mild to moderate COVID-19. Data have shown that the use ...Methylprednisolone is used to treat conditions such as arthritis, blood disorders, severe allergic reactions, certain cancers, eye conditions, skin / kidney /intestinal/ lung diseases, and immune ...Satisfaction. For me Cefdinir was worse than the infection. It felt like my entire digestive system had been chemically burned from my throat to intestines and bladder. It didn't feel like a UTI it felt like a chemical burn. It gave me a headache, stomach pain, belly pain and pain urinating.Azithromycin (AZM) is commonly used in Covid‐19 patients based on low‐quality evidence, increasing the risk of developing adverse events and antimicrobial resistance. The current systematic review and meta‐analysis investigated the safety and efficacy of AZM in treating Covid‐19 patients using published randomized controlled trials.Clindamycin. Cephalexin is a cephalosporin-type antibiotic that may be used in the treatment of infections caused by susceptible gram-positive bacteria. Approximately 10% of people who are allergic to penicillin... more. Clindamycin is an antibiotic that is usually reserved for treating anaerobic infections or other serious infections caused by ...Kory recommends a weekly dose of ivermectin to prevent COVID-19 infection. "He paints himself as a savior, which then implies that every other doctor is not a savior," Dr. Graham Walker, a San ...And, when used under the conditions described in the EUA to treat COVID-19, the known and potential benefits of baricitinib outweigh the known and potential risks for the drug. There are no ... Cefdinir for Pneumonia User Reviews. Cefdinir has an average rating of 5.9 out of 10 from a total of 15 reviews for the treatment of Pneumonia. 53% of reviewers reported a positive experience, while 40% reported a negative experience. Filter by condition.For infections: Adults and teenagers—300 milligrams (mg) every twelve hours or 600 mg once a day, taken for 5 to 10 days. Infants and children 6 months up to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 7 milligrams (mg) per kilogram (kg) of body weight every twelve hours or 14 ...f The use of another COVID-19 therapy may need to be considered. These immunosuppressants have significant drug-drug interaction potential with ritonavir, and they should not be used if close monitoring, including therapeutic drug monitoring (i.e., measuring drug concentration), is not feasible. Consult a patient’s specialist providers before ...Clindamycin. Cephalexin is a cephalosporin-type antibiotic that may be used in the treatment of infections caused by susceptible gram-positive bacteria. Approximately 10% of people who are allergic to penicillin... more. Clindamycin is an antibiotic that is usually reserved for treating anaerobic infections or other serious infections caused by ... Aug 4, 2023 · Common side effects of cefdinir may include: nausea, vomiting, stomach pain, diarrhea; vaginal itching or discharge; headache; or. rash (including diaper rash in an infant taking liquid cefdinir. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Therefore, in-keeping with its commitment to expediting the development and availability of potential COVID-19 treatments, the FDA issued an emergency use authorization on 1st May, 2020 for Remdesivir to be used for the treatment of suspected or laboratory-confirmed COVID-19 in adults and children hospitalized with severe disease (U.S. Food ...Uses. Cefdinir is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.This antibiotic treats ... Examples include ceftriaxone (Rocephin), piperacillin-tazobactam, cefepime (Maxipime ), ceftazidime (Fortaz) , vancomycin (Firvanq) , ciprofloxacin (Cipro), and levofloxacin (Levaquin). If you ...Jun 14, 2016 · TXA709 inhibits the function of FtsZ. Pilch said that TXA709 kills MRSA bacteria in a unique manner, inhibiting the function of a protein, FtsZ, essential for the bacteria to divide and survive. By combining TXA709 with cefdinir, a cephalosporin antibiotic that acts much like penicillin, scientists were able to lower the dosage of the new ... Dec 21, 2021 · Hydroxychloroquine. The drug hydroxychloroquine received a lot of attention at the beginning of the pandemic as a possible way to treat COVID-19. At one time used as an anti-malarial drug, it’s ... Methylprednisolone is used to treat conditions such as arthritis, blood disorders, severe allergic reactions, certain cancers, eye conditions, skin / kidney /intestinal/ lung diseases, and immune ...f The use of another COVID-19 therapy may need to be considered. These immunosuppressants have significant drug-drug interaction potential with ritonavir, and they should not be used if close monitoring, including therapeutic drug monitoring (i.e., measuring drug concentration), is not feasible. Consult a patient’s specialist providers before ...Our findings do not support the use of azithromycin in patients with mild-to-moderate COVID-19. We thank Jigar Patel and colleagues for their comments. The mean duration of symptoms at enrolment was 5·77 days (SD 3·49) in the azithromycin group and 6·27 days (3·55) in the standard care group. 19 (13%) of 147 participants in the azithromycin ...Oct 26, 2020 · Three drugs identified. After using LBVS to study approximately 4,000 drugs, then verifying their findings, the scientists identified three that may be effective against COVID-19 and, in their ... Jul 9, 2020 · Intervention and comparator: Eligible patients will be randomized to receive standard outpatient treatment only (group 1) or standard outpatient treatment plus prednisone (group 2). - Group 1: paracetamol 1 g/8 h (on demand) + hydroxychloroquine 400 mg/12h the first day, 200 mg/12 h for 4 days + azithromycin 500 mg/24h for 5 days.
We used GRADE to rate the certainty of evidence for the following primary outcomes: 1. to treat inpatients with moderate to severe COVID-19: mortality, clinical worsening defined as new need for intubation or death, clinical improvement defined as being discharged alive, quality of life, adverse and serious adverse events, and cardiac .... They can
Most patients with COVID-19 pneumonia present with a normal to low WBC count. Leukocytosis is a weak predictor of bacterial infection. In COVID-19 patients without leukocytosis, it is appropriate to withhold or discontinue antibiotics. Fever (T > 100.4 F) COVID-19 is a common cause of fever regardless of bacterial coinfection.Infectious (C. difficile-related) diarrhea: foul-smelling diarrhea, fever, nausea, frequent bowel movements (up to 15 times per day) The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.Methylprednisolone is used to treat conditions such as arthritis, blood disorders, severe allergic reactions, certain cancers, eye conditions, skin / kidney /intestinal/ lung diseases, and immune ... Most people who become ill with COVID-19 will be able to recover at home. Some of the same things you do to feel better if you have the flu — getting enough rest, staying well hydrated, and taking medications to relieve fever and aches and pains — also help with COVID-19. Beyond that, the FDA has also authorized treatments that may be used ...Jun 15, 2022 · Dexamethasone for COVID-19. Dexamethasone is a steroid drug that has been used for years to treat inflammation from many diseases including asthma, Crohn’s disease and certain cancers. Current guidelines recommend use of dexamethasone up to 10 days, or until discharge, for patients hospitalized with COVID-19. Dec 23, 2021 · Treatment of adults with a current diagnosis of mild-to-moderate COVID-19 who are at high risk for progression to severe COVID-19, including hospitalization or death and for Many medications are available to treat COVID-19, including oral treatments like Paxlovid (nirmatrelvir / ritonavir) and Lagevrio (molnupiravir). In late May 2023, the FDA fully approved Paxlovid for COVID-19. It’s the first oral antiviral that is approved to treat the condition. It was previously only available for emergency use.COVID-19 rashes. Skin rashes are now associated with coronavirus COVID-19 infections. Similar to other viral diseases such as HIV and bacterial diseases like syphilis, COVID-19 rashes can take many different forms. One study from Spain identified five different patterns of COVID-19 rash. The most common type was a "maculopapular rash."1. Introduction. The typical symptoms of coronavirus disease 2019 (COVID-19) pneumonia are fever, cough and dyspnea [].These symptoms may trigger clinicians to start empiric antibiotic treatment while waiting for diagnostic testing such as a SARS-CoV-2 polymerase chain reaction test, radiology and blood investigations.Jul 21, 2023 · f The use of another COVID-19 therapy may need to be considered. These immunosuppressants have significant drug-drug interaction potential with ritonavir, and they should not be used if close monitoring, including therapeutic drug monitoring (i.e., measuring drug concentration), is not feasible. Consult a patient’s specialist providers before ... Jan 9, 2023 · Infectious (C. difficile-related) diarrhea: foul-smelling diarrhea, fever, nausea, frequent bowel movements (up to 15 times per day) The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time. Chloroquine and nelfinavir were used as positive controls. Results: We revealed that the tested antibiotics exert strong capacity for binding to COVID-19 Main Protease (M pro). According to the results obtained from the GOLD docking program, ciprofloxacin and moxifloxacin bind to the protein active site more strongly than the native ligand. .